Starting as far back as the early 1700s, genetic deafness took a foothold on Martha’s Vineyard where as many as one in four residents were deaf and a majority of hearing residents also were able to communicate in what is considered one of the precursors to modern American Sign Language. Signs from the Mainland explores the deeper meaning and lessons to be learned from this unique enclave where deaf and hearing individuals coexisted seamlessly. Through interviews with historians, community members, and experts, the documentary reflects on the legacy of the MV Deaf community, the implications for the broader society, and its relevance to contemporary conversations about inclusivity and diversity.